Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury

Stimulation of Trigeminal Afferents Improves Motor Recovery After Facial Nerve Injury

AngličtinaMěkká vazbaTisk na objednávku
Skouras Emmanouil
Springer, Berlin
EAN: 9783642333101
Tisk na objednávku
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Podrobné informace

Recovery of mimic function after facial nerve transection is poor: the successful regrowth of axotomized motoneurons to their targets is compromised by (i) poor axonal navigation and excessive collateral branching, (ii) abnormal exchange of nerve impulses between adjacent regrowing axons and (iii) insufficient synaptic input to facial motoneurons. As a result, axotomized motoneurons get hyperexcitable and unable to discharge. Since improvement of growth cone navigation and reduction of the ephaptic cross-talk between axons turn out be very difficult, the authorsa concentrated on the third detrimental component and proposed that an intensification of the trigeminal input to axotomized electrophysiologically silent facial motoneurons might improve specificity of reinnervation. To test the hypothesis they compared behavioral, electrophysiological and morphological parameters after single reconstructive surgery on the facial nerve with those obtained after identical facial nerve surgery, but combined with direct or indirect stimulation of the ipsilateral infraorbital (ION) nerve.  The authors found that in all cases trigeminal stimulation was beneficial for the outcome by improving the quality of target reinnervation and recovery of vibrissal motor performance.
EAN 9783642333101
ISBN 3642333109
Typ produktu Měkká vazba
Vydavatel Springer, Berlin
Datum vydání 16. prosince 2012
Stránky 110
Jazyk English
Rozměry 235 x 155
Země Germany
Sekce Professional & Scholarly
Autoři Angelov Doychin N.; Bendella Habib; Pavlov, Stoyan; Skouras Emmanouil
Ilustrace XV, 110 p.
Edice 2013 ed.
Série Advances in Anatomy, Embryology and Cell Biology